By Anthony J.F. Griffiths, Susan R. Wessler, Sean B. Carroll, John Doebley
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Extra info for An Introduction to Genetic Analysis
In fact, for F I G U R E 1-17 A short segment of DNA from one of the chromosomes is shown. Each individual has two copies of the segment. In the mother, these are labeled M1 and M2; in the father, F1 and F2. The child inherited copy M1 from its mother and F2 from its father. The version of F2 in the child carries a new point mutation (red). Single nucleotide polymorphisms (SNPs) that distinguish the different copies are shown in green (mother) and purple (father). 3 Genetics Today 19 Number of new mutations observed The number of new point mutations increases with father’s age 100 F I G U R E 1-18 Plot of the number of new point mutations in each child (y-axis) by the age of the child’s father (x-axis).
The team seemed to have found the needle in a haystack for which they were looking; however, there was one last experiment to perform. The team needed to identify the specific defect in the defective CD73 gene that Benge and her siblings had inherited. ” The defective gene encoded only a short, or truncated, protein—it did not encode the complete sequence of amino acids. 3 Genetics Today 17 codons with letters TCG that encodes the amino acid serine was mutated to TAG, which signals the truncation of the protein.
How does the FR13A variety manage to survive submergence while many other types of rice cannot? FR13A has a different strategy that could be called sit tight. In response to complete submergence, rather than attempt rapid growth to escape the flood, an FR13A plant using the sit-tight strategy becomes quiescent. It stops the elongation growth response, thereby preventing itself from burning up all its reserve carbohydrates and becoming weak and spindly. With the sit-tight strategy, a plant can remain in a quiescent, submerged state for up to two weeks and then emerge healthy and resume normal growth when the flood waters recede.
An Introduction to Genetic Analysis by Anthony J.F. Griffiths, Susan R. Wessler, Sean B. Carroll, John Doebley