By Martin Stefan
This finished colour atlas covers the medical positive factors, etiology, pathophysiology, and remedy of schizophrenia together with smooth advancements in remedy and instructions of recent learn. It describes schizophrenia's profound results on conception, knowing, communique, and social habit; its identifiable antecedents in early mind progress and improvement; and morphological facts from structural mind imaging and autopsy reports. The atlas presents examples of the most recent study advancements in neuropsychology, psychophysiology and useful imaging in addition to in vivo receptor imaging and different advances in psychopharmacology.
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Additional resources for An Atlas of Schizophrenia
Patients with schizophrenia seem to be more vulnerable to significant harm at relatively lower levels of substance use. As substance misuse is so prevalent in the West, this is an area where secondary prevention of relapse could be focused. Social and psychological factors Psychosocial factors appear to contribute to both the onset and the relapse of schizophrenia. 13)20. The effect size is smaller than in depression and the time frame is somewhat shorter than in depression (where adverse life events are well ©2002 CRC Press LLC recognized etiological factors), with the 3 weeks prior to onset seeming to be the most important.
15) interact to propel the individual over a threshold for expression of the disease. 14 The differences in incidence in schizophrenia in people of African-Caribbean origin compared with those from other ethnic groups, in one study from Camberwell, South London. Figure reproduced with permission from Castle E, Wessely S, Der G, Murray RM. The incidence of operationally defined schizophrenia in Camberwell 1965–84. 15 There is no single cause of schizophrenia. Instead, like other complex disorders such as coronary heart disease, a number of genetic and environmental factors interact to cause the disease REFERENCES 1.
In the pathway shown, tyrosine hydroxylase is the rate-limiting enzyme. 8 Dopamine is metabolized by two enzymes. One, monoamine oxidase type B (MAO-B), is intraneuronal, and the other, catechol-O-methyl transferase (COMT), is extraneuronal. 7). Dopamine is metabolized by two enzymes; one, monoamine oxidase type B (MAO-B), is intraneuronal, and the other, catechol-O-methyl transferase (COMT), is extraneuronal. 8). Serotonin The serotonergic hypothesis of schizophrenia predates the dopaminergic hypothesis and stems from the finding by Woolley and Shaw in 195412 that the hallucinogen LSD acted via serotonin.
An Atlas of Schizophrenia by Martin Stefan